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All of the following statements about the M-protein of Group A- Streptococci are correct EXCEPT? A. The amino terminal portion (distal portion) is variable, accounting for over 80 distinct serotypes. B. M proteins allow streptococci to resist phagocytosis. C. Antibodies to M protein confer type-specific immunity. D. M protein is the major virulence factor of Group A streptococci E. M protein is the major constituent of the capsule of Group A streptococci
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A 12 year old boy presents with acute onset of sore throat, fever to 38.9 degrees C and painful anterior cervical lymphadenopathy. On exam the pharynx is red and swollen and the tonsils are covered with yellow-white exudates. The child also has halitosis. Which of the following non-suppurative complications are of concern? A. Sinusitis B. Acute rheumatic fever alone C. Acute glomerulonephritis alone D. Acute rheumatic fever and acute glomerulonephritis E. Scarlet fever alone
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Which of the following statements about Group B a streptococcus (Streptococcus agalactiae) is not correct? A. They are important causes of toxic strep syndrome. B. They are frequent colonizers of the female genital tract. C. Screening for this pathogen during pregnancy has reduced the incidence of neonatal sepsis. D. These organisms are b-hemolytic. E. They are important causes of urinary tract infections and bacteremia in elderly and diabetic adults.
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Which of the following statements about the 23-valent pneumococcal vaccine is not correct? A. It is a protein-conjugated, polysaccharide vaccine. B. It is poorly immunogenic in young children and immuno compromised hosts. C. It is routinely recommended for immune competent adults and children >2 yrs. of age at risk for serious pneumococcal disease. D. It protects against the major serotypes of pneumococci causing infection. E. An adult with asplenia would be a candidate for this vaccine.
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What is the O antigen of Enterobacteriaceae? A. Cell surface polysaccharide B. A channel controlling substance taken into the organism. C. A flagellar protein D. A peptidoglycan matrix important for cellular rigidity E. Cell wall lipopolysaccharide
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All Enterobacteriaceae share all of the following characteristics EXCEPT? A. Ferment glucose B. Reduce nitrates to nitrites C. Oxidase positive D. Gram negative E. Rod-shaped (bacilli)
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