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Anaphylaxis causes degranulation of basophils and mast cells?
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Anaphylaxis causes eosinophilia?
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Necrosis is a feature in tuberculosis.
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Necrosis is a feature in leprosy.
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Amyloid reacts with the Congo red stains.
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Describe the main difference between the hypothesis-testing and hypothesis-generating approaches to data mining.
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What are process measures in outcomes research and why are they sometimes used in place of actual outcomes data?
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What advantage does a pathologist have over investigators in most other fields in carrying out outcomes or data-mining studies?
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Define "association rules" and describe their use in exploratory data mining.
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What is the Arden syntax?
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You are working with an intensive care unit (ICU) attending physician on a project to see if you can predict readmission for patients with pancreatitis. You have access to a large database of ICU data (such as cardiac catheter values, vital signs, and respiratory parameters), as well as all of the data that can be gleaned from the LIS. There are approximately 800 measurements of various types for each of 4000 patients. You do not really have any specific ideas about what values would be most predictive; in fact, you think it is likely that the predictors are highly complex combinations of factors. Which of the 3 types of artificial intelligence systems would be most appropriate for this problem, and why?
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Rule-based systems underlie most clinical event monitors (programs that detect important clinical events and notify appropriate medical personnel). Often these systems work in conjunction with data from the clinical pathology LIS. What aspects of clinical pathology make a rule-based system a reasonable approach?
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Artificial intelligence and data-mining systems often use "training data sets" and "test data sets." Define these terms and describe briefly how these data sets are used.
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What are the benefits of high-throughput expression analysis in molecular biological investigations?
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What is a "gene expression signature" for a tumor?
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What is a forensic pathologist?
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What is a pathologist?
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